Recurrent ovarian cancer

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Treatment of recurrent ovarian cancer.

Recurrent ovarian cancer is a common clinical problem and the management of each patient must be individualized. Diagnosis is usually based on a progressively rising CA-125 titre, and a CT scan of the pelvis and abdomen, together with a chest X-ray should be performed in this situation. Although there is no study to support immediate treatment in the asymptomatic patient, our approach is to com...

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Bayesian Decision Analysis for Recurrent Ovarian Cancer

All cancers are usually classified further according to the extent or stage of disease so that therapies may be tailored to the particular disease stage. Moreover, detection of asymptomatic recurrences is associated with prolonged overall survival and survival from the time of initial detection of recurrence. This study applied Bayesian decision theorem to an inferential problem of recurrent ov...

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Treatment of recurrent epithelial ovarian cancer

Epidemiologic analysis reveals that the mortality rate from ovarian cancer is continuously decreasing due to the improvement of surgery and chemotherapy. However, the prognosis of ovarian cancer patients is still unsatisfactory overall considering that only 30% of patients are alive after five years. In fact, although surgery and first-line systemic chemotherapy induces complete and partial res...

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Management of Recurrent or Persistent Ovarian Cancer

Approximately 70-80% of patients with epithelial ovarian cancer will relapse after first-line chemotherapy with a platinum and taxane-based combination. These patients require further treatment and they may benefit from local and/or systemic therapy. The prognosis is poor and the management of relapsed ovarian cancer remains a difficult problem open to research [National Cancer Institute (NCI),...

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Carbon beam therapy in recurrent ovarian cancer.

Ovarian cancer results in more deaths than any other gynecologic malignancy. In the United States and Japan, there are >15 000 and 4000 deaths from ovarian cancer per year, respectively [1]. This high mortality rate can be attributed to 75% of patients who are diagnosed with stage III and IV disease with i.p. carcinomatosis [2]. Although the 5-year survival rate of patients in whom lymph nodes ...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2016

ISSN: 0923-7534

DOI: 10.1093/annonc/mdw079